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tailorMetrix
icoMetrix can draw upon its many years of clinical and quantitative image processing experience to tailor the most optimal solution to your advanced image processing needs. Our team combines its vast experience in clinical research, necessary to thoroughly understand the problem, with the in-depth computer and medical image processing skills necessary to provide the best solution. Our range of experiences spans all modalities, pre-clinical and clinical imaging, and a wide range of image processing methods.
Therapeutic areas we have recently been working on are neurology, oncology, psychiatry, orthopedics, pre-clinical imaging, ...
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Example: Longitudinal Registration for Local Strain Mapping
In bone tissue engineering, researchers look for the scaffold that, seeded with osteogenic cells, leads to optimal bone formation. As proliferation and differentiation of the cells is also promoted by mechanical strains caused by the deformation of the structures to which the cells attach, the local strain distribution inside bone tissue engineering (TE) scaffolds on which the cells are seeded can influence cell behaviour and subsequent bone formation. Together with researchers from the Katholieke Universiteit Leuven specialized in material and skeletal tissue engineering, we have developed a method to non-invasively evaluate the local strain distribution inside the scaffolds, based upon a combined use of micro-CT and in-situ loading. The novel local strain mapping approach was based upon image registration of the micro-CT scans at different loading steps using icoMetrix proprietary non-rigid image registration method.
G. Kerckhofs, S. Van Bael, M. Moesen, F. Maes, D. Loeckx, J. Schrooten, M. Wevers, Novel micro-CT-based local strain mapping tool to characterize the failure modes of bone tissue engineering scaffolds, SkyScan user meeting, April 22-24, 2009, Ghent, Belgium (Best presentation award)